Publications

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Publications in PubMed


2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002

2012

  • Bagaria, A., Jaravine, V., Huang, Y. J., Montelione, G. T. & Güntert, P. Protein structure validation by generalized linear model RMSD prediction. Protein Sci. 21, 229–238 (2012)
  • Busche, A., Gottstein, D., Hein, C., Ripin, N., Pader, I., Tufar, P., Eisman, E. B., Gu, L. Walsh, C. T., Sherman, D. H., Löhr, F., Güntert, P. & Dötsch, V. Characterization of the interaction between an ACP domain and a halogenase in the curacin A polyketide synthetase. ACS Chem. Biol., published online ahead of print.
  • He, F., Inoue, M., Kigawa, T., Takahashi, M., Kuwasako, K., Tsuda, K., Kobayashi, N., Terada, T., Shirouzu, M., Tanaka, A., Sugano, S., Güntert, P., Yokoyama, S. & Muto, Y. Solution structure of the Splicing Factor Motif (SFM) of the human Prp18 protein. Proteins 80, 968–974 (2012)
  • Rosato, A., Aramini, J. M., Arrowsmith, C., Bagaria, A., Baker, D., Cavalli, A., Doreleijers, J. F., Eletsky, A., Giachetti, A., Guerry, P., Gutmanas, A., Güntert, P., He. Y. F., Herrmann, T., Huang, Y. J., Jaravine, V., Jonker, H. R. A., Kennedy, M. A., Lange, O. F., Liu, G., Malliavin, T. E., Mani, R., Mao, B., Montelione, G. T., Nilges, M., Rossi, P., van der Schot, G., Schwalbe, H., Szyperski, T., Vendruscolo, M., Vernon, R., Vranken, W. F., de Vries, S., Vuister, G. W., Wu, B. Yang, Y. & Bonvin, A. M. J. J. Blind testing of routine, fully automated determination of protein structures from NMR data. Structure 20, 227–236 (2012)

2011

  • Barthelmes, K., Reynolds, A. M., Peisach, E., Jonker, H. R., DeNunzio, N. J., Allen, K. N., Imperiali, B. & Schwalbe, H. Engineering encodable lanthanide-binding tags into loop regions of proteins. J. Am. Chem. Soc. 133, 808-819 (2011)
  • Cohen, L. S., Arshava, B., Neumoin, A., Becker, J. M., Güntert, P., Zerbe, O. & Naider, F. Comparative NMR analysis of an 80-residue G protein-coupled receptor fragment in two membrane mimetic environments. Biochim. Biophys. Acta 1808, 2674–2684 (2011)
  • Deutsch, G. B., Zielonka, E. M., Coutandin, D., Weber, T.A., Schäfer, B., Hannewald, J., Luh, L. M., Durst, F. G., Ibrahim, M., Hoffmann, J., Niesen, F. H., Sentürk, A., Kunkel, H., Brutschy, B., Schleiff, E., Knapp, S., Acker-Palmer, A., Grez, M., McKeon, F. & Dötsch V. DNA Damage in Oocytes Induces a Switch of the Quality Control Factor TAp63α from Dimer to Tetramer. Cell 44, 566-576 (2011)
  • Englert, N. E., Richter, C., Wiesner, J., Hintz, M., Jomaa, H. & Schwalbe H. NMR Studies of DOXP reductoisomerase and its inhibitor complex. Chembiochem 12, 468-476 (2011)
  • Güntert, P. Automated structure determination from NMR Spectra. In Advances in Biomedical Spectroscopy. Volume 3: Biomolecular NMR Spectroscopy (Eds. A. Dingley & S. Pascal), IOS Press, Amsterdam, pp. 338–365 (2011)
  • Hänsel, R., Löhr, F., Foldynová-Trantírková, S., Bamberg, E., Trantírek, L. & Dötsch, V. The parallel G-quadruplex structure of vertebrate telomeric repeat sequences is not the preferred folding topology under physiological conditions. Nucleic Acids Res. Epub ahead of print (2011)
  • Hefke, F., Bagaria, A., Reckel, S., Ullrich, S.J., Dötsch, V., Glaubitz, C. & Güntert P. Optimization of amino acid type-specific 13C and 15N labeling for the backbone assignment of membrane proteins by solution- and solid-state NMR with the UPLABEL algorithm. J. Biomol. NMR 49, 75-84 (2011)
  • Hempelmann, F., Hölper, S., Verhoefen, M. K., Woerner, A. C., Köhler, T., Fiedler, S. A., Pfleger, N., Wachtveitl, J. & Glaubitz, C. His75-Asp97 Cluster in Green Proteorhodopsin. J. Am. Chem. Soc. 133, 4645-4654 (2011)
  • Ikeya, T., Jee. J. G., Shigemitsu, Y., Hamatsu, J., Mishima, M., Ito, Y., Kainosho, M. & Güntert, P. Exclusively NOESY-based automated NMR assignment and structure determination of proteins. J. Biomol. NMR. 50, 137–146 (2011)
  • Jonker, H. R., Baumann, S., Wolf, A., Schoof, S., Hiller, F., Schulte, K. W., Kirschner, K. N., Schwalbe, H & Arndt, H. D. NMR Structures of Thiostrepton Derivatives for Characterization of the Ribosomal Binding Site. Angew. Chem. Int. Ed. Engl. 50, 3308-3312 (2011)
  • Knehans, T., Schüller, A., Doan, D. N., Nacro, K., Hill, J., Güntert, P., Madhusudhan, M.S, Weil, T. & Vasudevan, S. G. Structure-guided fragment-based in silico drug design of dengue protease inhibitors. J. Comput. Aided Mol. Des. 25, 263-274 (2011)
  • Kodama, Y., Reese, M. L., Shimba, N., Ono, K., Kanamori, E., Dötsch, V., Noguchi, S., Fukunishi, Y., Suzuki, E. I., Shimada, I. & Takahashi H. Rapid identification of protein-protein interfaces for the construction of a complex model based on multiple unassigned signals by using time-sharing NMR measurements. J. Struct. Biol. Epub ahead of print (2011)
  • Meyer, B., Wurm, J. P., Kötter, P., Leisegang, M. S., Schilling, V., Buchhaupt, M., Held, M., Bahr, U., Karas, M., Heckel, A., Bohnsack, M. T., Wöhnert, J. & Entian, K. D. The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of ψ1191 in yeast 18S rRNA. Nucleic Acids Res. 39, 1526-1537 (2011)
  • Reckel, S., Gottstein, D., Stehle, J., Löhr, F., Verhoefen, M. K., Takeda, M., Silvers, R., Kainosho, M., Glaubitz, C., Wachtveitl, J., Bernhard, F., Schwalbe, H., Güntert, P. & Dötsch, V. Solution NMR structure of proteorhodopsin. Angew. Chem. Int. Ed. 50, 11942–11946 (2011)
  • Rozenknop, A., Rogov, V. V., Löhr, F., Güntert, P., Dikic, I., & Dötsch, V. Characterization of the interaction of GABARAPL-1 with the LIR motif of NBR1. J. Mol. Biol. 410, 477–487 (2011)
  • Schmöe, K., Rogov, V. V., Rogova, N. Y., Löhr, F., Güntert, P., Bernhard, F. & Dötsch, V. Structural insights into Rcs phosphotransfer: the newly identified RcsD-ABL domain enhances interaction with the response regulator RcsB. Structure 19, 577-587 (2011)
  • Siemoneit, U., Koeberle, A., Rossi, A., Dehm, F., Verhoff, M., Reckel, S., Maier, T. J., Jauch, J., Northoff, H., Bernhard, F., Dötsch, V., Sautebin, L., Werz, O. Inhibition of microsomal prostaglandin E-2 synthase-1 as a molecular basis for the anti-inflammatory actions of boswellic acids from frankincense. Brit. J. Pharmacol. 162, 147-162 (2011)
  • Sripathomsawat, W., Tanpaiboon, P., Heering, J., Dötsch, V., Hennekam, R.C. & Kantaputra, P. Phenotypic analysis of Arg227 mutations of TP63 with emphasis on dental phenotype and micturition difficulties in EEC syndrome. Am. J. Med. Genet. A 155, 228-232 (2011)
  • Taylor, G. F., Wood, S. P., Mörs, K., Glaubitz, C., Werner, J. M. & Williamson, P. T. F. Morphological differences between β2-Microglobulin in fibrils and inclusion bodies. Chembiochem 12, 556-558 (2011)
  • Tsuda, K., Someya, T., Kuwasako, K., Takahashi, M., He, F., Unzai, S., Inoue, M., Harada, T., Watanabe, S., Terada, T., Kobayashi, N., Shirouzu, M., Kigawa, T., Tanaka, A., Sugano, S., Güntert, P., Yokoyama, S. & Muto, Y. Structural basis for the dual RNA-recognition modes of human Tra2-β RRM. Nucleic Acids Res. 39, 1538-1553 (2011)
  • Ullrich, S. J., Hellmich, U. A., Ullrich, S. & Glaubitz, C. Interfacial enzyme kinetics of a membrane bound kinase analyzed by real-time MAS-NMR. Nat. Chem. Biol. 7, 263-270 (2011)
  • Wassenaar, T. A., van Dijk, M., Loureiro-Ferreira, N., van der Schot, G., de Vries, S. J., Schmitz, C., van der Zwan, J., Boelens, R., Giachetti, A., Ferella, L., Rosato, A., Bertini, I., Herrmann, T., Jonker, H. R. A., Bagaria, A., Jaravine, V., Güntert, P., Schwalbe, H., Vranken, W. F., Doreleijers, J. F., Vriend, G., Vuister, G. W., Franke, D., Kikhney, A., Svergun, D. I., Fogh, R., Ionides, J., Laue, E. D., Spronk, C., Verlato, M., Badoer, S., Dal Pra, S., Mazzucato, M., Frizziero, E. & Bonvin, A. M. J. J. WeNMR: Structural biology on the Grid. Proceedings of IWSG-Life2011 (2011)
  • Yamashita, S., Nagata, T., Kawazoe, M., Takemoto, C., Kigawa, T, Güntert, P., Kobayashi, N., Terada, T., Shirouzu, M., Wakiyama, M., Muto, Y. & Yokoyama, S. Structures of the first and second double-stranded RNA-binding domains of human TAR RNA-binding protein. Protein Sci. 20, 118-130 (2011)
  • Zutz, A., Hoffmann, J., Hellmich, U.A., Glaubitz, C., Ludwig, B., Brutschy, B. & Tampe, R. Asymmetric ATP hydrolysis cycle of the heterodimeric multidrug ABC transport complex TmrAB from Thermus thermophilus. J. Biol. Chem. 286, 7104-7115 (2011)

2010

  • Arias-Cartin, R., Lyubenova, S., Ceccaldi, P., Prisner, T., Magalon, A., Guigliarelli, B. & Grimaldi, S. HYSCORE evidence that endogenous Mena- and Ubisemiquinone bind at the Same Q Site (QD) of Escherichia coli nitrate reductase A. J. Am. Chem. Soc. 132, 5942-5943 (2010)
  • Beko, S. L., Thomas S. D., Brüning, J., Alig, E., van de Streek, J, Lakatos, A., Glaubitz, C. & Schmidt, M. U. X-ray powder diffraction, solid-state NMR and dispersion-corrected DFT calculations to investigate the solid-state structure of 2-ammonio-5-chloro-4-methylbenzenesulfonate. Zeitschrift für Kristallographie 225, 382-387 (2010)
  • Buck, J., Noeske, J., Wöhnert, J. & Schwalbe, H. Dissecting the influence of Mg2+ on 3D architecture and ligand-binding of the guanine-sensing riboswitch aptamer domain. Nucleic Acids Res. 38, 4143-4153 (2010)
  • Dastvan, R., Bode, B. E., Karuppiah, M. P., Marko, A., Lyubenova, S., Schwalbe, H. & Prisner, T. F. Optimization of transversal relaxation of nitroxides for pulsed electron-electron double resonance spectroscopy in phospholipid membranes. J. Phys. Chem. B 114, 13507-13516 (2010)
  • Doller, A., Schlepckow, K., Schwalbe, H., Pfeilschifter, J. & Eberhardt, W. Tandem phosphorylation of serines 221 and 318 by protein kinase Cδ coordinates mRNA binding and nucleocytoplasmic shuttling of HuR. Mol. Cell. Biol. 30, 1397-1410 (2010)
  • Duchardt-Ferner, E., Weigand, J.E., Ohlenschläger, O., Schmidtke, S.R., Suess, B. & Wöhnert, J. Highly Modular Structure and Ligand Binding by Conformational Capture in a Minimalistic Riboswitch. Angew. Chem. Int. Ed. Engl. 49, 6216-6219 (2010)
  • Elgán, T.H., Planson, A.G., Beckwith, J., Güntert, P. & Berndt, K.D. Determinants of activity in glutaredoxins: an in vitro evolved Grx1-like variant of Escherichia coli Grx3. Biochem. J. 430, 487-495 (2010)
  • Gafurov, M., Lyubenova, S., Denysenkov, V., Ouari, O., Karoui, H., Le Moigne, F., Tordo, P. & Prisner, T. EPR Characterization of a Rigid Bis-TEMPO-Bis-Ketal for Dynamic Nuclear Polarization. Appl. Magn. Reson. 37, 505-514 (2010)
  • Gerum, C., Schlepckow, K. & Schwalbe, H. The unfolded state of the murine prion protein and properties of single-point mutants related to human prion diseases. J. Mol. Biol. 401, 7-12 (2010)
  • Grimaldi, S., Arias-Cartin, R., Lanciano, P., Lyubenova, S., Endeward, B., Prisner, T.F., Magalon, A. & Guigliarelli, B. Direct evidence for nitrogen ligation to the high stability semiquinone intermediate in Escherichia coli nitrate reductase A. J. Biol. Chem. 285, 179-187 (2010)
  • Grimaldi, S., Arias-Cartin, R., Lyubenova, S., Lanciano, P., Endeward, B., Prisner, T.F., Magalon, A. & Guigliarelli, B. EPR-HYSCORE study of quinone binding in respiratory nitrate reductase: Molecular basis for the adaptation to anaerobiosis-aerobiosis transition. BBA-Bioenergetics 1797, 114-114 (2010)
  • Hähnke, M.J., Richter, C., Heinicke, F. & Schwalbe, H. The HN(COCA)HAHB NMR experiment for the stereospecific assignment of Hβ-protons in non-native states of proteins. J. Am. Chem. Soc. 132, 918-919 (2010)
  • Hagarman, A., Measey, T., Mathieu, D., Schwalbe, H. & Schweitzer-Stenner, R. Intrinsic propensities of amino acid residues in GXG peptides inferred from amide I´ band profiles and NMR scalar coupling constants. J. Am. Chem. Soc. 132, 540-551 (2010)
  • Hamada, T., Matsunaga, S.,Fujiwara, M., Fujita, K., Hirota, H., Schmucki, R., Güntert, P. & Fusetani, N. Solution Structure of Polytheonamide B, a Highly Cytotoxic Nonribosomal Polypeptide from Marine Sponge. J. Am. Chem. Soc. 132, 12941-12945 (2010)
  • Handa, Y., Hikawa, Y., Tochio, N., Kogure, H., Inoue, M., Koshiba, S., Güntert, P., Inoue, Y., Kigawa, T., Yokoyama, S. & Nameki, N. Solution structure of the mitochondrial protein ICT1 that is essential for cell vitality. J. Mol. Biol. 404, 260-273 (2010)
  • He, F., Umehara, T., Saito, K., Harada, T., Watanabe, S., Yobuki, T., Kigawa, T., Takahashi, M., Kuwasako, K., Tsuda, K., Matsuda, T., Aoki, M., Seki, E., Kobayashi, N., Güntert, P., Yokoyama, S. & Muto, Y. Structural Insight into the Zinc Finger CW Domain as a Histone Modification Reader. Structure 18, 1127-1139 (2010)
  • Hoffmann, J., Aslimovska, L., Bamann, C., Glaubitz, C., Bamberg, E. & Brutschy, B. Studying the stoichiometries of membrane proteins by mass spectrometry: microbial rhodopsins and a potassium ion channel. Phys. Chem. Chem. Phys. 12, 3480-3485 (2010)
  • Hoffmann, M., Lopez, J. J., Pergola, C., Feisst, C., Pawelczik, S., Jakobsson, P-J., Sorg, B. L., Glaubitz, C., Steinhilber, D. & Werz, O. Hyperforin induces Ca2+-independent arachidonic acid release in human platelets by facilitating cytosolic phospholipase A(2) activation through select phospholipid interactions. Bba. Mol. Cell Biol. L. 1801, 462-472 (2010)
  • Ikeya, T., Sasaki, A., Sakakibara, D., Shigemitsu, Y., Hamatsu, J., Hanashima, T., Mishima, M., Yoshimasu, M., Hayashi, N., Mikawa, T., Nietlispach, D., Wälchli, M., Smith, B. O., Shirakawa, M., Güntert, P. & Ito, Y. NMR protein structure determination in living E. coli cells using nonlinear sampling. Nature Protocols 5, 1051–1060 (2010)
  • Junge, F., Luh, L. M. , Proverbio, D., Schäfer, B., Abele, R., Beyermann, M., Dötsch, V. & Bernhard, F. Modulation of G-protein coupled receptor sample quality by modified cell-free expression protocols: A case study of the human endothelin A receptor. J. Struct. Biol. 172, 94-106 (2010)
  • Kai, L., Kaldenhoff, R., Lian, J., Zhu, X., Dötsch, V., Bernhard, F., Cen, P. & Xu, Z. Preparative scale production of functional mouse aquaporin 4 using different cell-free expression modes. PLoS One 5, e12972 (2010)
  • Koeberle, A., Rossi, A., Zettl, H., Pergola, C.,Dehm, F., Bauer, J., Greiner, C., Reckel, S.,Hoernig, C., Northoff, H., Bernhard, F., Dötsch, V.,Sautebin, L., Schubert-Zsilavecz, M. & Werz, O. The molecular pharmacology and in vivo activity of 2-(4-Chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS121), a dual inhibitor of microsomal prostaglandin E-2 Synthase-1 and 5-Lipoxygenase. J. Pharmacol. Exp. Ther. 332, 840-848 (2010)
  • Krstić, I., Frolow, O., Sezer, D., Endeward, B., Weigand, J. E., Suess, B., Engels, J.W. & Prisner, T.F. PELDOR spectroscopy reveals preorganization of the neomycin-responsive riboswitch tertiary structure. J. Am. Chem. Soc. 132, 1454-1455 (2010)
  • Kumar, J., Sreeramulu, S., Schmidt, T.L., Richter, C., Vonck, J., Heckel, A., Glaubitz, C. & Schwalbe, H. Prion protein amyloid formation involves structural rearrangements in the C-terminal domain. Chembiochem. 11, 1208-1213 (2010)
  • Ledwidge, R., Hong, B., Dötsch, V. & Miller, S. M. NmerA of Tn501 Mercuric Ion Reductase: Structural Modulation of the pK(a) Values of the Metal Binding Cysteine Thiols. Biochemistry 49, 8988-8998 (2010)
  • Lyubenova, S., Maly, T., Zwicker, K., Brandt, U., Ludwig, B. & Prisner, T. Multifrequency pulsed electron paramagnetic resonance on metalloproteins. Acc. Chem. Res. 43, 181-189 (2010)
  • Marko, A., Margraf, D., Cekan, P., Sigurdsson, S. T., Schiemann, O. & Prisner, T. F. Analytical method to determine the orientation of rigid spin labels in DNA. Phys. Rev. E 81, 021911 (2010)
  • Maslennikov, I., Klammt, C., Hwang, E., Kefala, G., Okamura, M., Esquivies, L., Mörs, K., Glaubitz, C., Kwiatkowski, W., Jeon, Y.H. & Choe, S. Membrane domain structures of three classes of histidine kinase receptors by cell-free expression and rapid NMR analysis. Proc. Natl. Acad. Sci. USA 107, 10902-10907 (2010)
  • Novak, I., Kirkin V., McEwan, D. G., Zhang, J., Wild, P., Rozenknop, A., Rogov, V., Löhr, F., Popovic, D., Occhipinti, A., Reichert, A.S., Terzic, J., Dötsch, V., Ney P.A. & Dikic, I. Nix is a selective autophagy receptor for mitochondrial clearance. EMBO Reports 11, 45-51 (2010)
  • Nozinovic, S., Fürtig, B., Jonker, H. R. A., Richter, C. & Schwalbe, H. High-resolution NMR structure of an RNA model system: the 14-mer cUUCGg tetraloop hairpin RNA. Nucleic Acids Res. 38, 683-694 (2010)
  • Nozinovic, S., Richter, C., Rinnenthal, J., Fürtig, B., Duchardt-Ferner, E., Weigand, J. E., Schwalbe, H. Quantitative 2D and 3D Gamma-HCP experiments for the determination of the angles alpha and zeta in the phosphodiester backbone of oligonucleotides. J. Am. Chem. Soc. 132, 10318-10329 (2010)
  • Reckel, S., Sobhanifar, S., Durst, F., Löhr, F., Shirokov, V. A., Dötsch, V. & Bernhard, F. Strategies for the cell-free expression of membrane proteins. Methods Mol Biol. 607, 187-212 (2010)
  • Richter, C., Kovacs, H., Buck, J., Wacker, A., Fürtig, B., Bermel, W. & Schwalbe, H. 13C-direct detected NMR experiments for the sequential J-based resonance assignment of RNA oligonucleotides. J. Biomol. NMR 47, 259-269 (2010)
  • Rinnenthal, J., Klinkert, B., Narberhaus, F. & Schwalbe, H. Direct observation of the temperature-induced melting process of the Salmonella fourU RNA thermometer at base-pair resolution. Nucleic Acids Res. 38, 3834-3847 (2010)
  • Saxena, K., Schieborr, U., Anderka, O., Duchardt-Ferner, E., Elshorst, B., Gande, S. L., Janzon, J., Kudlinzki, D., Sreeramulu, S., Dreyer, M. K., Wendt, K.U., Herbert, C., Duchaussoy, P., Bianciotto, M., Driguez, P.A., Lassalle, G., Savi, P., Mohammadi, M., Bono, F. & Schwalbe, H. Influence of heparin mimetics on the assembly of the FGF - FGFR4 signaling complex. J. Biol. Chem. 285, 26628-26640 (2010)
  • Schmidtke, S. R., Duchardt-Ferner, E., Weigand, J.E., Suess, B. & Wöhnert, J. NMR resonance assignments of an engineered neomycin-sensing riboswitch RNA bound to ribostamycin and tobramycin. Biomol. NMR Assign. 4, 115-118 (2010)
  • Schwarz, D., Daley, D., Beckhaus, T., Dötsch, V. & Bernhard, F. Cell-free expression profiling of E. coli inner membrane proteins. Proteomics 10, 1762-1779 (2010)
  • Sobhanifar, S., Reckel, S., Junge, F., Schwarz, D., Kai, L., Karbyshev, M., Löhr, F., Bernhard, F. & Dötsch, V. Cell-free expression and stable isotope labelling strategies for membrane proteins. J. Biomol. NMR 46, 33-43 (2010)
  • Sobhanifar, S., Schneider, B., Löhr, F., Gottstein, D., Ikeya, T., Filipek, S., Güntert, P., Bernhard, F. & Dötsch, V. Structural investigation of the C-terminal catalytic fragment of presenilin-1. Proc. Natl. Acad. Sci. USA 107, 9644–9649 (2010)
  • Straub, W.E., Weber, T.A., Schäfer, B., Candi, E., Durst, F., Ou, H.D., Rajalingam, K., Melino, G. & Dötsch, V. The C-terminus of p63 contains multiple regulatory elements with different functions. Cell Death & Disease 1, e5 (2010)
  • Weigand, J. E., Schmidtke, S. R., Will, T. J., Duchardt-Ferner, E., Hammann, C., Wöhnert, J & Suess, B. Mechanistic insights into an engineered riboswitch: a switching element which confers riboswitch activity. Nucleic Acids Resn. Published online ahead of print
  • Wurm, J.P., Meyer, B., Bahr, U., Held, M., Frolow, O., Kotter, P., Engels, J.W., Heckel, A., Karas, M., Entian, K.D. & Wöhnert, J. The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase. Nucleic Acids Res. 38, 2387-2398 (2010)

2009

  • Altmann, K.H., Buchner, J., Kessler, H., Diederich, F., Kräutler, B., Lippard, S., Liskamp, R., Müller, K., Nolan, E.M., Samori, B., Schneider, G., Schreiber, S.L., Schwalbe, H., Toniolo, C., van Boeckel, C.A.A., Waldmann, H. & Walsh, C.T. The state of the art of chemical biology. ChemBioChem, 10, 16-29 (2009)
  • Buck, J., Li, Y.L., Richter, C., Vergne, J., Maurel, M.C. & Schwalbe, H. NMR spectroscopic characterization of the adenine-dependent hairpin ribozyme. ChemBioChem, 10, 2100-2110 (2009)
  • Busche, A.E., Aranko, A.S., Talebzadeh-Farooji, M., Bernhard, F., Dötsch, V. & Iwai, H. Segmental isotopic labeling of a central domain in a multidomain protein by protein trans-splicing using only one robust DnaE intein. Angew. Chem. Int. Ed., 48, 6128-6131 (2009)
  • Coutandin, D., Löhr, F., Niesen, F. H., Ikeya, T., Weber, T. A., Schäfer, B., Bullock, A. N., Yang, A., Güntert, P. , Knapp, S., McKeon, F., Der Ou, H. & Dötsch, V. Conformational stability and activity of p73 require a second helix in the tetramerization domain. Cell Death Diff., 16, 1582–1589 (2009)
  • Endeward, B., Butterwick, J.A., MacKinnon, R. & Prisner, T.F. Pulsed electron−electron double-resonance determination of spin-label distances and orientations on the tetrameric potassium ion channel KcsA. J. Am. Chem. Soc., 131, 15246–15250 (2009)
  • Ferner, J., Suhartono, M., Breitung, S., Jonker, H.R.A., Hennig, M., Wöhnert, J., Göbel, M. & Schwalbe, H. Structures of HIV TAR RNA-ligand complexes reveal higher binding stoichiometries. ChemBioChem, 10, 1490-1494 (2009)
  • Foldynova-Trantirkova, S., Matulova, J., Dötsch, V., Löhr, F., Cirstea, I., Alexandov, K., Breitling, R., Lukes, J. & Trantirek, L. A cost-effective amino-acid-type selective isotope labeling of proteins expressed in Leishmania tarentolae. J. Biomol. Struct. Dyn., 26, 755-762 (2009)
  • Hänsel, R., Foldynová-Trantírková, S., Löhr, F., Buck, J., Bongartz, E., Bamberg, E., Schwalbe, H., Dötsch, V. & Trantírek, L. Evaluation of parameters critical for observing nucleic acids inside living Xenopus laevis oocytes by in-cell NMR spectroscopy. Am. Chem. Soc., 131, 15761-15768 (2009)
  • He, F., Dang, W., Abe, C., Tsuda, K., Inoue, M., Watanabe, S., Kobayashi, N., Kigawa, T, Matsuda, T., Yabuki, T., Aoki, M., Seki, E., Harada, T., Tomabechi, Y., Terada, T., Shirouzu, M., Tanaka, A., Güntert, P., Muto, Y. & Yokoyama, S. Solution structure of the RNA binding domain in the human muscleblind-like protein 2. Protein Sci., 18, 80-91 (2009)
  • He, F., Dang, W., Saito, K., Watanabe, S., Kobayashi, N., Güntert, P., Kigawa, T, Tanaka, A., Muto, Y. & Yokoyama, S. Solution structure of the cysteine-rich domain in Fn14, a member of the tumor necrosis factor receptor superfamily. Protein Sci., 18, 650–656 (2009)
  • He, F., Saito, K., Kobayashi, N., Harada, T., Watanabe, S., Kigawa, T, Güntert, P., Unzai, S., Muto, Y. & Yokoyama, S. Structural and functional characterization of the NHR1 domain of the Drosophila Neuralized E3 ligase in the Notch signaling pathway. J. Mol. Biol., 393, 478-495 (2009)
  • Hellmich, U.A., Pfleger, N. & Glaubitz, C. 19F-MAS NMR on proteorhodopsin: Enhanced protocol for site-specific labeling for general application to membrane proteins. Photochem. Photobiol., 85, 535-539 (2009)
  • Hermann, F.G, Egerer, L., Brauer, F., Gerum, C., Schwalbe, H., Dietrich, U. & von Laer, D. Mutations in gp120 contribute to the resistance of human immunodeficiency virus type 1 to membrane-anchored C-peptide maC46. J. Virol., 83, 4844-4853 (2009)
  • Ikeya, T., Takeda, M., Yoshida, H., Terauchi, T., Jee, J., Kainosho, M. & Güntert, P. Automated NMR structure determination of stereo-array isotope labeled ubiquitin from minimal sets of spectra using the SAIL-FLYA system. J. Biomol. NMR, 44, 261-272 (2009)
  • Juhnke, H.D., Hiltscher, H., Nasiri, H.R., Schwalbe, H. & Lancaster, C.R.D. Production, characterization and determination of the real catalytic properties of the putative 'succinate dehydrogenase' from Wolinella succinogenes. Mol. Microbiol., 71, 1088-1101 (2009)
  • Khayrutdinov, B.I., Bae, W.J., Yun, Y.M., Lee, J.H., Tsuyama, T., Kim, J.J., Hwang, E., Ryu, K.S., Cheong, H.K., Cheong, C., Ko, J.S., Enomoto, T., Karplus, P.A., Güntert, P., Tada, S., Jeon, Y.H. & Cho, Y. Structure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factors. Prot. Sci., 18, 2252-2264 (2009)
  • Lörinczi, E., Verhoefen, M.K., Wachtveitl, J., Woerner, A.C., Glaubitz, C., Engelhard, M., Bamberg, E. & Friedrich, T. Voltage- and pH-dependent changes in vectoriality of photocurrents mediated by wild-type and mutant proteorhodopsins upon expression in Xenopus Oocytes. J. Mol. Biol., 393, 320–341 (2009)
  • Maier, T.J., Schiffmann, S., Wobst, I., Birod, K., Angioni, C., Hoffmann, M., Lopez, J.J., Glaubitz, C., Steinhilber, D., Geisslinger, G. & Grösch, S. Cellular membranes function as a storage compartment for celecoxib. J. Mol. Med., 87, 981–993 (2009)
  • Manoharan, V., Fürtig, B., Jäschke, A. & Schwalbe, H. Metal-induced folding of diels-alderase ribozymes studied by static and time-resolved NMR spectroscopy. J. Am. Chem. Soc., 131, 6261-6270 (2009)
  • Margraf, D., Schuetz, D., Prisner, T.F. & Bats, J.W. Biphenyl-4,4'-diyl bis(2,2,5,5-tetramethyl-1-oxyl-3-pyrroline-3-carboxylate). Acta Cryst., E65, o1784 (2009)
  • Marko, A., Margraf, D., Yu, H., Mu, Y., Stock, G. & Prisner, T. Molecular orientation studies by pulsed electron-electron double resonance experiments. J. Chem. Physics, 130, 064102 (2009)
  • Matsuki, Y., Maly, T., Ouari, O., Karoui, H., Le Moigne, F., Rizzato, E., Lyubenova, S., Herzfeld, J., Prisner, T., Tordo, P. & Griffin, R.G. Dynamic nuclear polarization with a rigid biradical. Angew. Chem. Int. Ed., 121, 27, 5096-5100 (2009)
  • Nasiri, H.R., Panisch, R., Madej, M.G., Bats, J.W., Lancaster, C.R.D. & Schwalbe, H. The correlation of cathodic peak potentials of vitamin K3 derivatives and their calculated electron affinities. The role of hydrogen bonding and conformational changes. Biochim. Biophys. Acta, 1787, 601-608 (2009)
  • Ohnishi, S. Pääkkönen, K., Koshiba, S., Tochio, N., Sato, M., Kobayashi, N., Harada, T., Watanabe, S., Muto, Y., Güntert, P., Tanaka, A., Kigawa, T. & Yokoyama, S. Solution structure of the GUCT domain from human RNA helicase II/Guβ reveals the RRM fold, but implausible RNA interactions. Proteins, 74, 133–144 (2009)
  • Pedò, M., Löhr, F., D'Onofrio, M., Assfalg, M., Dötsch, V. & Molinari, H. NMR studies reveal the role of biomembranes in modulating ligand binding and release by intracellular bile acid binding proteins. J. Mol. Biol., 394, 852-863 (2009)
  • Peroza, E.A., Schmucki, R., Güntert, P., Freisinger, E. & Zerbe O. The βE-domain of Ec-1 metallothionein: A metal-binding domain with a distinctive structure. J. Mol. Biol., 387, 207–218 (2009)
  • Pfleger, N., Woerner, A.C., Yang, J., Shastri, S., Hellmich, U.A., Aslimovska, L., Maier, M.S.M. & Glaubitz, C. (2009) Solid-state NMR and functional studies on proteorhodopsin. BBA Bioenergetics., 1787,697-705 (2009)
  • Rakhmatullin, R.M., Kurkin, I.N., Mamin, G.V., Orlinskii, S.B., Gafurov, M.R., Baibekov, E.I., Malkin, B.Z., Gambarelli, S. & Barbara, B. Coherent spin manipulations in Yb3+: CaWO4 at X- and W-band EPR frequencies. Physical Review, B 79, 172408 (2009)
  • Rehm, S., Han, S., Hassani, I., Sokocevic, A., Jonker, H.R.A., Engels, J.W. & Schwalbe, H. The high resolution NMR structure of parvulustat (Z-2685) from Streptomyces parvulus FH-1641: Comparison with tendamistat from Streptomyces tendae 4158. ChemBioChem, 10, 119-127 (2009)
  • Rinnenthal, J., Richter, C., Nozinovic, S., Fürtig, B., Lopez, J.J., Glaubitz, C. & Schwalbe, H. RNA phosphodiester backbone dynamics of a perdeuterated cUUCGg tetraloop RNA from phosphorus-31 NMR relaxation analysis. J. Biomol. NMR, 45, 143-155 (2009)
  • Rinnenthal, J. & Schwalbe, H. HNHC: a triple resonance experiment for correlating the H2, N1(N3) and C2 resonances in adenine nucleobases of 13C-, 15N-labeled RNA oligonucleotides. J. Biomol. NMR, 44, 101-105 (2009)
  • Rosato, A., Bagaria, A., Baker, D., Bardiaux, B., Cavalli, A., Doreleijers, J.F., Giachetti, A., Guerry, P., Güntert, P., Herrmann, T., Huang, Y.J., Jonker, H.R.A., Mao, B., Malliavin, T.E., Montelione, G.T., Nilges, M., Raman, S., van der Schot, G., Vranken, W., Vuister, G.W. & Bonvin, A.M.J.J. CASD-NMR: a rolling experiment for the critical assessment of automated structure determination of proteins from NMR data. Nature Methods 6, 625–626 (2009)
  • Sakakibara, D., Sasaki, A., Ikeya, T., Hamatsu, J., Hanashima, T., Mishima, M., Yoshimasu, M., Hayashi, N., Mikawa, T., Wälchli, M., Smith, B.O., Shirakawa, M., Güntert, P. & Ito, Y. Protein structure determination in living cells by in-cell NMR spectroscopy. Nature, 458, 102-105 (2009)
  • Schäfer, G., Shastri, S., Verhoefen, M.K., Vogel, V., Glaubitz, C., Wachtveitl, J. & Mäntele, W. Characterizing the structure and photocycle of PR 2D crystals with CD-and FTIR spectroscopy. Photochem Photobiol., 85, 529-534 (2009)
  • Schiemann, O., Cekan, P., Margraf, D., Prisner, T.F. & Sigurdsson, S.T. Relative orientation of rigid nitroxides by PELDOR: Beyond distance measurements in nucleic acids. Angew. Chem. Int. Ed., 48, 3292-3295 (2009)
  • Schmucki, R., Yokoyama, S. & Güntert, P. Automated assignment of NMR chemical shifts using peak-particle dynamics simulation with the DYNASSIGN algorithm. J. Biomol. NMR, 43, 97-109 (2009)
  • Sezer, D., Gafurov, M, Prandolini, M.J., Denysenkov, V.P. & Prisner, T.F. Dynamic nuclear polarization of water by a nitroxide radical: Rigorous treatment of the electron spin saturation and comparison with experiments at 9.2 Tesla. Phys. Chem. Chem. Phys., 11, 6638-6653 (2009)
  • Sreeramulu, S., Jonker, H.R.A., Langer, T., Richter, C., Lancaster, C.R.D. & Schwalbe, H. The human Cdc37 center dot Hsp90 complex studied by heteronuclear NMR spectroscopy. J. Biol. Chem., 284, 3885-3896 (2009)
  • Sreeramulu, S., Gande, S.L., Göbel, M. & Schwalbe, H. Molecular mechanism of inhibition of the human protein complex Hsp90-Cdc37, a kinome chaperone-cochaperone, by triterpene celastrol. Angew. Chem. Int. Ed., 48, 5853-5855 (2009)
  • Tayefeh, S., Kloss, Thomas., Kreim, M., Gebhardt, M., Baumeister, D., Hertel, B., Richter, C., Schwalbe, H., Moroni, A., Thiel, G. & Kast S.M. Model development for the viral Kcv potassium channel. Biophysical J., 96, 485-498(2009)
  • Tsuda, K., Kuwasako, K., Takahashi, M., Someya, T., Inoue, M., Terada, T., Kobayashi, N., Shirouzu, M., Kigawa, T., Tanaka, A., Sugano, S., Güntert, P., Muto, Y. & Yokoyama, S. Structural basis for the sequence specific RNA-recognition mechanism of human CUG-BP1 RRM3. Nucl. Acids Res. 37, 5151–5166 (2009)
  • Verhoefen, M.K., Neumann, K., Weber, I., Glaubitz, C. & Wachtveitl, J. Primary reaction dynamics of proteorhodopsin mutant D97N observed by femtossecond infrared and visible spectroscopy. Photochem. Photobiol., 85, 540-546 (2009)
  • Villa, A., Wöhnert, J. & Stock, G. Molecular dynamics simulation study of the binding of purine bases to the aptamer domain of the guanine sensing riboswitch. Nucl. Acids Res. 37, 4774–4786 (2009)
  • Wurm, J.P., Duchardt, E., Meyer, B.,Leal, B.Z., Kötter, P., Entian, K.D. & Wöhnert, J. Backbone resonance assignments of the 48 kDa dimeric putative 18S rRNA-methyltransferase Nep1 from Methanocaldococcus jannaschii. Biomol. NMR Assign., 3, 251-254 (2009)

2008

  • Basting, D., Lorch, M., Lehner, I. & Glaubitz, C. Transport cycle intermediate in small multidrug resistance protein is revealed by substrate fluorescence. FASEB J., 22, 365-373 (2008)
  • Breitung, S.T., Lopez, J.J., Dürner, G., Glaubitz, C., Göbel, M.W. & Suhartono, M. A practical synthesis of the 13C/15N-labelled tripeptide N-formyl-Met-Leu-Phe, useful as a reference in solid-state NMR spectroscopy. Beilstein Journal of Organic Chemistry, 4 (2008)
  • Bode, B.E., Plackmeyer, J., Prisner, T.F. & Schiemann, O. PELDOR measurements on a nitroxide-labeled Cu(II) porphyrin: Orientation selection, spin-density distribution, and conformational flexibility. J. Phys. Chem., A 112, 5064-5073 (2008)
  • Cramer, N., Helbig, S., Baro, A., Laschat, S., Diestel, R., Sasse, F., Mathieu, D., Richter, C., Kummerlöwe, G., Luy, B. & Schwalbe, H. Synthesis and biological properties of cylindramide derivatives: Evidence for calcium-dependent cytotoxicity of tetramic acid lactams. ChemBioChem, 9, 2474-2486 (2008)
  • Cuzic, S., Heidemann, K.A., Wöhnert, J. & Hartmann, R.K. Escherichia coli RNase P RNA: Substrate ribose modifications at G+1, but not nucleotide -1/+73 bass pairing, affect the transition state for cleavage chemistry. J. Mol. Biol., 379, 1-8 (2008)
  • Dietz, J., Koch, J., Kaur, A., Raja, C., Stein, S., Grez, M., Pustowka, A., Mensch, S., Ferner, J., Möller, L., Bannert, N., Tampé, R., Divita, G., Mély, Y., Schwalbe, H. & Dietrich, U. Inhibition of HIV-1 by a peptide ligand of the genomic RNA packaging signal Ψ. Chemmedchem, 3, 749-755 (2008)
  • Ferner, J., Villa, A., Duchardt, E., Widjajakusuma, E., Wöhnert, J., Stock, G. & Schwalbe, H. NMR and MD studies of the temperature-dependent dynamics of RNA YNMG-tetraloops. Nucl. Acids Res., 36, 1928-1940 (2008)
  • Furtig, B., Richter, C., Schell, P., Wenter, P., Pitsch, S. & Schwalbe, H. NMR-spectroscopic characterization of phosphodiester bond cleavage catalyzed by the minimal hammerhead ribozyme. RNA Biology, 5, 41-48 (2008)
  • Gieldon, A., Lopez, J.J., Glaubitz, C. & Schwalbe, H. Theoretical study of the human bradykinin-bradykinin B2 receptor complex. ChemBioChem, 9, 2487-2497 (2008)
  • Göbel, M.W., Dürner, G., Lopez, J.L., Breitung, S.T., Suhartono, M. & Glaubitz, C. A practical synthesis of the 13C/15N-labelled tripeptide N-Formyl-Met-Leu-Phe, useful as a reference in solid-state NMR spectroscopy. Beilstein J. Org. Chem., 4,35 (2008)
  • Hellmich, U.A., Haase, W., Velamakanni, S., van Veen, H.W. & Glaubitz, C. Caught in the act: ATP hydrolysis of an ABC-multidrug transporter followed by real-time magic angle spinning NMR. FEBS Lett., 582, 3557-3562 (2008)
  • Höfer, P., Carl, P., Guthausen, G., Prisner, T., Reese, M., Carlomagno, T., Griesinger, C. & Bennati, M. Studies of dynamic nuclear polarization with nitroxides in aqueous solution. Appl. Magn. Reson., 34, 393-398 (2008)
  • Keller, T., Schwarz, D., Bernhard, F., Dötsch, V., Hunte, C., Gorboulev, V. & Koepsell, H. Cell free expression and functional reconstitution of eukaryotic drug transporters. Biochemistry, 47, 4552-4564 (2008)
  • Klyszejko, A.L., Shastri, S., Mari, S.A., Grubmüller, H., Müller, D.J. & Glaubitz, C. Folding and assembly of proteorhodopsin. J. Mol. Biol., 376, 35-41 (2008)
  • Koglin, A., Löhr, F., Bernhard, F., Rogov, V.R., Frueh, D.P., Strieter, E.R., Mofid, M.R., Güntert, P., Wagner, G., Walsh, C.T., Marahiel, M.A. & Dötsch, V. Structural basis for the selectivity of the external thioesterase of the surfactin-synthetase. Nature, 454, 907–911 (2008)
  • Koller, A.N., Schwalbe, H. & Gohlke, H. Starting structure dependence of NMR order parameters derived from MD simulations: Implications for judging force-field quality. Biophys. J., 95, L4-L6 (2008)
  • Kuwasako, K., Dohmae, N., Inoue, M., Shirouzu, M., Taguchi, S., Güntert, P., Séraphin, B., Muto, Y. & Yokoyama, S. Complex assembly mechanism and an RNA-binding mode of the human p14-SF3b155 spliceosomal protein complex identified by NMR solution structure and functional analyses. Proteins, 71, 1617–1636 (2008)
  • Kuwasako, K., Takahashi, M., Tochio, N., Abe, C., Tsuda, K., Inoue, M., Terada, T., Shirouzu, M., Kobayashi, N., Kigawa, T., Taguchi, S., Tanaka, A., Hayashizaki, Y., Güntert, P., Muto, Y. & Yokoyama, S. Solution structure of the second RNA recognition motif (RRM) domain of murine T cell intracellular antigen-1 (TIA-1) and its RNA recognition mode. Biochemistry, 47, 6437–6450 (2008)
  • Lehner, I., Basting, D., Meyer, B., Haase, W., Manolikas, T., Kaiser, C., Karas, M. & Glaubitz, C. The key residue for substrate transport (Glu(14)) in the EmrE dimer is asymmetric. J. Biol. Chem., 283, 3281-3288 (2008)
  • Lin, Y J., Umehara, T., Inoue, M., Saito, K., Kigawa, T., Jang, M.K., Ozato, K., Yokoyama, S., Padmanabhan, B. & Güntert, P. Solution structure of the extraterminal domain of the bromodomain-containing protein BRD4. Protein Sci., 17, 2174–2179 (2008)
  • Lopez, J.J., Kaiser, C., Shastri, S. & Glaubitz, C. Double quantum filtering homonuclear MAS NMR correlation spectra: A tool for membrane protein studies. J. Biomol. NMR, 41, 97-104 (2008)
  • Lopez, J.J., Shukla, A.K., Reinhart, C., Schwalbe, H., Michel, H. & Glaubitz, C. The structure of the neuropeptide bradykinin bound to the human G-protein coupled receptor bradykinin B2 as determined by solid-state NMR spectroscopy. Angew. Chem. Int. Ed., 47, 1668-1671 (2008)
  • Nagata, T., Suzuki, S., Endo, R., Shirouzu, M., Terada, T., Inoue, M., Kigawa, T, Güntert, P., Hayashizaki, Y., Muto, Y. & Yokoyama, S. The RRM domain of poly(A)-specific ribonuclease (PARN) has a non-canonical binding site for mRNA cap analog recognition. Nucl. Acids Res., 36, 4754–4767 (2008)
  • Neumann, K., Verhoefen, M.K., Weber, I., Glaubitz, C. & Wachtveitl, J. Initial reaction dynamics of proteorhodopsin observed by femtosecond infrared and visible spectroscopy. Biophys. J., 94, 4796-4807 (2008)
  • Nielsen, G., Stadler, M., Jonker, H., Betz, M. & Schwalbe, H NMR spectroscopy in chemical biology. Enzyclopedia in Chemical Biology (2008)
  • Noeske, J., Buck, J., Wöhnert, J. & Schwalbe, H Ligand binding and conformational changes in the purine-binding riboswitch aptamer domains. In Non-Protein Coding RNA (Ed. N. Walter, S.A. Woodson, R.T. Batey) (2008)
  • Nören-Müller, A., Wilk, W., Saxena, K., Schwalbe, H., Kaiser, M. & Waldmann, H. Discovery of a new class of inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B by biology-oriented synthesis. Angew. Chem. Int. Ed., 47, 5973-5977 (2008)
  • Pellecchia, M., Bertini, I., Cowburn, D., Dalvit, C., Giralt, E., Jahnke, W., James, T.L., Homans, S.W., Kessler, H., Luchinat, C., Meyer, B., Oschkinat, H., Peng, J., Schwalbe, H. & Siegal, G. Perspectives on NMR in drug discovery: a technique comes of age. Nature Reviews Drug Discovery, 7, 738-745 (2008)
  • Pfleger, N., Lorch, M., Woerner, A.C., Shastri, S. & Glaubitz, C. Characterisation of Schiff base and chromophore in green proteorhodopsin by solid-state NMR. J. Biomol. NMR, 40, 15-21 (2008)
  • Prandolini, M.J., Denysenkov, V.P., Gafurov, M., Lyubenova, S., Endeward, B., Bennati, M. & Prisner, T.F. First DNP results from a liquid water-TEMPOL sample at 400 MHz and 260 GHz. Appl. Magn. Reson., 34, 399-407 (2008)
  • Prisner, T. & Kockenberger, W. Dynamic nuclear polarization: New experimental and methodology approaches and applications in physics, chemistry, biology and medicine. Appl. Magn. Reson., 34, 213-218 (2008)
  • Reckel, S., Sobhanifar, S., Schneider, B., Junge, F., Schwarz, D., Durst, F., Löhr, F., Güntert, P., Bernhard, F. & Dötsch, V. Transmembrane segment enhanced labeling as a tool for the backbone assignment of α-helical membrane proteins. Proc. Natl. Acad. Sci. USA, 105, 8262–8267 (2008)
  • Schlepckow, K., Wirmer, J., Bachmann, A., Kiefhaber, T. & Schwalbe, H. Conserved folding pathways of α-lactalbumin and lysozyme revealed by kinetic CD, fluorescence, NMR, and interrupted refolding experiments. J. Mol. Biol., 378, 686-698 (2008)
  • Schroeder, C., Werner, K., Otten, H., Krätzig, S., Schwalbe, H. & Essen, L.O. Influence of a joining helix on the BLUF domain of the YcgF photoreceptor from Escherichia coli. ChemBioChem, 9, 2463-2473 (2008)
  • Schwalbe, H. & Fürtig, B. Nucleic acids from A to Z. Wiley-VCH (2008)
  • Takeda, M., Chang, C.K., Ikeya, T., Güntert, P., Chang, Y.H., Hsu, Y.L., Huang, T.H. & Kainosho, M. Solution structure of the C-terminal dimerization domain of SARS coronavirus nucleocapsid protein determined by the SAIL-NMR method. J. Mol. Biol., 380, 608–622 (2008)
  • Takeda, M., Sugimori, N., Torizawa, T., Terauchi, T., Ono, A.M., Yagi, H., Yamaguchi, Y., Kato, K., Ikeya, T., Jee, J., Güntert, P., Aceti, D.J., Markley, J.L. & Kainosho, M. Structure of the putative 32 kDa myrosinase binding protein from Arabidopsis (At3g16450.1) as determined by the SAIL-NMR method. FEBS J., 275, 5873–5884 (2008)
  • Taylor, A.B., Meyer, B., Leal, B.Z., Köttter, P., Schirf, V., Demeler, B., Hart, P.J., Entian, K.D. & Wöhnert, J. The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site. Nucl. Acids Res., 36, 1542-1554 (2008)
  • Wagner, S., Carpentier, I., Rogov, V., Kreike, M., Ikeda, F., Löhr, F., Wu, C.J., Ashwell, J.D., Dötsch, V., Dikic, I. & Beyaert, R. Ubiquitin binding mediates the NF-kappa B inhibitory potential of ABIN proteins. Oncogene, 27, 3739-3745 (2008)
  • Werner, K., Richter, C., Klein-Seetharaman, J. & Schwalbe, H. Isotope labeling of mammalian GPCRs in HEK293 cells and characterization of the C-terminus of bovine rhodopsin by high resolution liquid NMR spectroscopy. J. Biomol. NMR, 40, 49-53 (2008)
  • Yoshida, H., Furuya, N., Lin, Y.J., Güntert, P., Komano, T. & Kainosho, M. Structural basis of the role of the NikA ribbon-helix-helix domain in initiating bacterial conjugation. J. Mol. Biol., 384, 690–701 (2008)

2007

  • Bode, B.E., Margraf, D., Plackmeyer, J., Dürner, G., Prisner, T.F. & Schiemann, O., Counting the monomers in nanometer-sized oligomers by pulsed electron-electron double resonance. J. Am. Chem. Soc., 129, 6736-6745 (2007)
  • Corrêa, I.R., Nören-Müller, A., Ambrosi, H.D., Jakupovic, S., Saxena, K., Schwalbe, H., Kaiser, M. & Waldmann, H. Identification of inhibitors for mycobacterial protein tyrosine phosphatase B (MptpB) by biology-oriented synthesis (BIOS). Chemistry-an Asian Journal, 2, 1109-1126 (2007)
  • Der Ou, H., Löhr, F., Vogel, V., Mantele, W. & Dötsch, V. Structural evolution of C-terminal domains in the p53 family. EMBO J., 26, 3463-3473 (2007)
  • Dikanovo, S.A., Hollan, J.T., Endeward, B., Kolling, D.R.J., Samoilova, R.I., Prisner, T.F. & Crofts, A.R. Hydrogen bonds between nitrogen donors and the semiquinone in the Q(i)-site of the bc(1) complex. J. Biol. Chem., 282, 25831-25841 (2007)
  • Diller, A., Roy, E., Gast, P., van Gorkom, H.J., de Groot, H.J.M., Glaubitz, C., Jeschke, G., Matysik, J. & Alia, A. 15N photochemically induced dynamic nuclear polarization magic-angle spinning NMR analysis of the electron donor of photosystem II. Proc. Natl. Acad. Sci. USA, 104, 12767-12771 (2007)
  • Duchardt, E., Sigalov, A.B., Aivazian, D., Stern, L.J. & Schwalbe, H. Structure induction of the T-cell receptor zeta-chain upon lipid binding investigated by NMR spectroscopy. ChemBioChem, 8, 820-827 (2007)
  • Fürtig, B., Buck, J., Manoharan, V., Bermel, W., Jäschke, A., Wenter, P., Pitsch, S. & Schwalbe, H. Time-resolved NMR studies of RNA folding. Biopolymers, 86, 360-383 (2007)
  • Fritscher, J., Hrobarik, P. & Kaupp, M. Computational studies of electron paramagnetic resonance parameters for paramagnetic molybdenum Complexes. 1. Method validation on small and medium-sized systems. J. Phys. Chem. B, 111, 4616-4629 (2007)
  • Fritscher, J., Hrobarik, P. & Kaupp, M. Computational studies of EPR parameters for paramagnetic molybdenum complexes. II. Larger MoV systems relevant to molybdenum enzymes. Inorg. Chem., 46, 8146-8161 (2007)
  • Haber-Pohlmeier, S., Abarca-Heidemann, K., Körschen, H.G., Dhiman, H.K., Heberle, J., Schwalbe, H., Klein-Seetharaman, J., Kaupp, U.B. & Pohlmeier, A. Binding of Ca2+ to glutamic acid-rich polypeptides from the rod outer segment. Biophys. J., 92, 3207-3214 (2007)
  • Hoeller, D., Hecker, C.M., Wagner, S., Rogov, V., Dötsch, V. & Dikic, I. E3-independent monoubiquitination of ubiquitin-binding proteins. Mol. Cell, 26, 891-898 (2007)
  • Ikeda, F., Hecker, C.M., Rozenknop, A., Nordmeier, R.D., Rogov, V., Hofmann, K., Akira, S., Dötsch, V. & Dikic, I. Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes. EMBO J., 26, 3451-3462 (2007)
  • Ikeya, T., Güntert, P. & Kainosho, M. NMRによる蛋白質構造決定の自動化. In 計算シミュレーションと分析データ解析, Maruzen, Tokyo, pp. 148–166 (2007) (in Japanese)
  • Jonker, H.R.A., Ilin, S., Grimm, S.K., Wöhnert, J. & Schwalbe, H. L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy. Nucleic Acids Res., 35, 441-454 (2007)
  • Klammt, C., Schwarz, D., Dötsch, V. & Bernhard, F. Cell-free production of integral membrane proteins on a preparative scale. Methods Mol Biol., 375, 57-78 (2007)
  • Klammt, C., Schwarz, D., Eifler, N., Engel, A., Piehler, J., Haase, W., Hahn, S., Dötsch, V. & Bernhard, F. Cell-free production of G protein-coupled receptors for functional and structural studies. J. Struct. Biol., 158, 482-493 (2007)
  • Klammt, C., Srivastava, A., Eifler, N., Junge, F., Beyermann, M., Schwarz, D., Michel, H., Doetsch, V. & Bernhard, F. Functional analysis of cell-free-produced human endothelin B receptor reveals transmembrane segment 1 as an essential area for ET-1 binding and homodimer formation. FEBS J., 274, 3257-69 (2007)
  • Löhr, F., Hänsel, R., Rogov, V.V. & Dötsch, V. Improved pulse sequences for sequence specific assignment of aromatic proton resonances in proteins. J. Biomol. NMR, 37, 205-224 (2007)
  • Lopez, J.J., Mason, A.J., Kaiser, C. & Glaubitz, C. Separated local field NMR experiments on oriented samples rotating at the magic angle. J. Biomol. NMR, 37, 97-111 (2007)
  • Ludwig, V., Krebs, A., Stoll, M., Dietrich, U., Ferner, J., Schwalbe, H., Scheffer, U., Dürner, G. & Göbel, M.W. Tripeptides from synthetic amino acids block the Tat-TAR association and slow down HIV spread in cell cultures. ChemBioChem, 8, 1850-1856 (2007)
  • Lyubenova, S., Siddiqui, M.K., de Vries, M.J.M.P., Ludwig, B. & Prisner, T.F. Protein-protein interactions studied by EPR relaxation measurements: Cytochrome c and cytochrome c oxidase. J. Phys. Chem., B 111, 3839-3846 (2007)
  • Margraf, D., Bode, B.E., Marko, A., Schiemann, O. & Prisner, T.F. Conformational flexibility of nitroxide biradicals determined by X-band PELDOR experiments. Mol. Phys., 105, 2153-2160 (2007)
  • Martin, L.J., Hähnke, M.J., Nitz, M., Wöhnert, J., Silvaggi, N.R., Allen, K.N., Schwalbe, H. & Imperiali, B. Double-lanthanide-binding tags: Design, photophysical properties, and NMR applications. J. Am. Chem. Soc., 129, 7106-7113 (2007)
  • Noeske, J., Buck, J., Fürtig, B., Nasiri, H.R., Schwalbe, H. & Wöhnert, J. Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch. Nucleic Acids Res., 35, 572-583 (2007)
  • Obolensky, O.I., Schlepckow, K., Schwalbe, H. & Solov'yov, A.V. Theoretical framework for NMR residual dipolar couplings in unfolded proteins. J. Biomol. NMR, 39, 1-16 (2007)
  • Rinnenthal, J., Richter, C., Ferner, J., Duchardt, E. & Schwalbe, H. Quantitative Γ-HCNCH: Determination of the glycosidic torsion angle χ in RNA oligonucleotides from the analysis of CH dipolar cross-correlated relaxation by solution NMR spectroscopy. J. Biomol. NMR, 39, 17-29 (2007)
  • Rogov, V.V., Löhr, F., Rogova, N., Klammt, C., Koglin, A., Bernhard, F. & Dötsch, V. NMR assignment of 1H, 13C and 15N resonances of the truncated Escherichia coli RcsC (700-949), including the phosphoreceiver domain. J. Biomol. NMR, 38, 165-165 (2007)
  • Schiemann, O., Carmieli, R. & Goldfarb, D. W-band 31P-ENDOR on the high-affinity Mn2+-binding site in the minimal and tertiary stabilized hammerhead ribozymes. Appl. Magn. Reson., 31, 543-552 (2007)
  • Schiemann, O., Piton, N., Plackmeyer, J., Bode, B.E., Prisner, T.F. & Engels, J.W. Spin labeling of oligonucleotides with the nitroxide TPA and use of PELDOR, a pulse EPR method, to measure intramolecular distances. Naｔure Protocols, 2, 904-923 (2007)
  • Schwarz, D., Junge, F., Durst, F., Frölich, N., Schneider, B., Reckel, S., Sobhanifar, S., Dötsch, V. & Bernhard, F. Preparative scale expression of membrane proteins in Escherichia coli-based continuous exchange cell-free systems. Nature Protocols, 2, 2945-2957 (2007)
  • Schwarz, D., Klammt, C., Koglin, A., Löhr, F., Schneider, B., Dötsch, V. & Bernhard, F. Preparative scale cell-free expression systems: New tools for the large scale preparation of integral membrane proteins for functional and structural studies. Methods, 41, 355-369 (2007)
  • Siarheyeva, A., Lopez, J.J., Lehner, I., Hellmich, U.A., van Veen, H.W. & Glaubitz, C. Probing the molecular dynamics of the ABC multidrug transporter LmrA by deuterium solid-state nuclear magnetic resonance. Biochemistry, 46, 3075-3083 (2007)
  • Silvaggi, N.R., Martin, L.J., Schwalbe, H., Imperiali, B. & Allen, K.N. Double-lanthanide-binding tags for macromolecular crystallographic structure determination. J. Am. Chem. Soc., 129, 7114-7120 (2007)
  • Werner, K., Lehner, I., Dhiman, H.K., Richter, C., Glaubitz, C., Schwalbe, H., Klein-Seetharaman, J. & Khorana, H.G. Combined solid state and solution NMR studies of α,ε-15N labeled bovine rhodopsin. J. Biomol. NMR, 37, 303-312 (2007)

2006

  • Ab, E., Atkinson, A.R., Banci, L., Bertini, I., Ciofi-Baffoni, S., Brunner, K., Diercks, T., Dötsch, V., Engelke, F., Folkers, G.E., Griesinger, C., Gronwald, W., Günther, U., Habeck, M., de Jong, R.N., Kalbitzer, H.R., Kieffer, B., Leeflang, B.R., Loss, S., Luchinat, C., Marquardsen, T., Moskau, D., Neidig, K.P., Nilges, M., Piccioli, M., Pierattelli, R., Rieping, W., Schippmann, T., Schwalbe, H., Trave, G., Trenner, J., Wöhnert, J., Zweckstetter, M. & Kaptein, R. NMR in the SPINE structural proteomics project. Acta Crystallogr. D., Biol. Crystallogr., 62, 1150-1161 (2006)
  • Batra-Safferling, R., Heidemann, K.A., Körschen, H. Gerd., Tziatzios, C., Stoldt, M., Budyak, I., Willbold, D., Schwalbe, H., Klein-Seetharaman, J. & Kaupp, U.B. Glutamic acid-rich proteins of rod photoreceptors are natively unfolded. J. Biol. Chem., 281, 1449-1460 (2006)
  • Betz, M., Vogtherr, M., Schieborr, U., Elshorst, B., Grimme, S., Pescatore, B., Langer, T., Saxena, K. & Schwalbe, H. Chemical biology of kinases studied by NMR spectroscopy in chemical biology - from small molecules to systems biology and drug design. [edited by T. Kapoor, S. Schreiber and G. Wess (2006)]
  • Bennati, M., Hertel, M., Fritscher, J., Prisner, T.F., Weiden, N., Hofweber, R., Spörner, M., Horn, G. & Kalbitzer, H.R. High-frequency 94 GHz ENDOR characterization of the metal binding site in wild-type Ras GDP and its oncogenic mutant G12V in frozen solution. Biochemistry, 45, 42-50 (2006)
  • Cramer, N., Buchweitz, M., Laschat, S., Frey, W., Mathieu, D., Richter, C. & Schwalbe, H. Total synthesis and NMR investigations of cylindramide. Chem. Eur. J., 12, 2488-2503 (2006)
  • Denysenkov, V.P., Prisner, T.F., Stubbe, J. & Bennati, M. High-field pulsed electron–electron double resonance spectroscopy to determine the orientation of the tyrosyl radicals in ribonucleotide reductase. Proc. Nat. Acad. Sci. 103(36), 13386 - 13390 (2006)
  • Dikanov, S.A., Kolling, D.R.J., Endeward, B., Samoilova, R.I., Prisner, T.F., Nair, S.K. & Crofts, A.R. Identification of hydrogen bonds to the rieske cluster through the weakly coupled nitrogens detected by electron spin echo envelope modulation spectroscopy. J. Biol. Chem.,281, 27416-27425 (2006)
  • Fritscher, J., Prisner, T.F. & MacMillan, F. Theoretical investigation of QA–• ligand interactions in bacterial reaction centers of rhodobacter sphaeroides. Appl. Magn. Reson., 30, 251-268 (2006)
  • Jacobs, D.M., Langner, T., Elshorst, B., Saxena, K., Fiebig, K.M., Vogtherr, M. & Schwalbe, H. NMR backbone assignment of the N-terminal domain of human HSP90. J. Biomol. NMR, 36, 52-52 (2006)
  • Kainosho, M., Torizawa, T., Iwashita, Y., Terauchi, T., Ono, A. M. & Güntert, P. Optimal isotope labeling for NMR protein structure determinations. Nature 440, 52–57 (2006)
  • Kelly, A.E., Kranitz, H., Dötsch, V. & Mullins, R.D. Actin binding to the C domain of WASP/Scar proteins plays a critical role in the activation of the Arp2/3 complex. J. Biol. Chem., 281, 10589-10597 (2006)
  • Klammt, C., Schwarz, D, Löhr, F., Schneider, B., Dötsch, V. & Bernhard, F. Preparative scale cell-free expression systems: New tools for the large scale preparation of integral membrane proteins for functional and structural studies. FEBS J., 273, 4141-4153 (2006)
  • Koglin, A., Klammt, C., Trbovic, N., Schwarz, D., Schneider, B., Schäfer, B. Löhr, F., Bernhard, F. & Dötsch, V. Combination of cell-free expression and NMR spectroscopy as a new approach for structural investigation of membrane proteins. Magn. Reson. Chem., 44, 17-23 (2006)
  • Koglin, A., Mofid, M.R., Löhr, F., Schäfer, B., Rogov, V.V., Blum, M.M., Mittag, T., Marahiel, M.A., Bernhard, F. & Dötsch, V. Conformational switches modulate protein interactions in peptide antibiotic synthetases. Science, 312, 273-276 (2006)
  • Landrieu, I., Lacosse, L., Leroy, A., Wiesruszeski, J.-M., Trivelli, X., Sibille, N., Schwalbe, H., Saxena, K., Langer, T. & Lippens, G. NMR analysis of a tau phosophorylation pattern. JACS, 128, 3575-3583 (2006)
  • Lerner, H.-W., Margraf, G., Kretz, T., Schiemann, O., Bats, J.W., Dürner, G., de Biani, F.F., Zanello, P., Bolte, M. & Wagner, M. Redox behaviour of pyrazolyl-substituted 1,4-dihydroxyarenes: Formation of the corresponding semiquinones, quinhydrones and quinone. Z. Naturforsch. 61b, 252-264 (2006)
  • Nomura, A.M., Marnett, A.B., Shimba, N., Dötsch, V. & Craik, C.S. One functional switch mediates reversible and irreversible inactivation of a herpesvirus protease. Biochemistry, 45, 3572-3579 (2006)
  • Madej, M.G., Nasiri, H.R., Hilgendorff, N.S., Schwalbe, H. & Lancaster, C.R.D. Evidence for transmembrane proton transfer in a dihaem-containing membrane protein complex. EMBO J., 25, 4963-4970 (2006)
  • Madej, M.G., Nasiri, H.R., Hilgendorff, N.S., Schwalbe, H., Unden, G. & Lancaster, C.R.D. Experimental evidence for proton motive force-dependent catalysis by the diheme-containing succinate: Menaquinone oxidoreductase from the gram-positive bacterium Bacillus licheniformis. Biochemistry, 45, 15049-15055 (2006)
  • Maly, T., Grgic, L., Zwicker, K., Zickermann, V., Brand, U. & Prisner, T.F. Cluster N1 of complex I from Yarrowia lipolytica studied by pulsed EPR spectroscopy. J. Biol. Inorg. Chem.,11, 343-350 (2006)
  • Müller, D., Krick, A., Kehraus, S., Hart, M., Küpper, F.C., Prinz, H., Janning, P., Waldmann, H., Saxena, K., Schwalbe, H. & König, G.M. Brunsvicamide A-C, sponge-related cyanobacterial peptides with Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory activity. J. Med. Chem., 49, 4871-4878 (2006)
  • Nasiri, H.R., Bolte, M., Lorch, M. & Schwalbe, H. Crystal structure of 4-hexyl-4 '-hydroxyazobenzene isopropanol hemisolvate, C18H22N2O center dot 1/2C(3)H(8)O. Z. Kristallogr. NCS 221, 219-220 (2006)
  • Nasiri, H.R., Bolte, M. & Schwalbe, H. Tautomerism of 4-hydroxy-4(1H) quinolon. [Het. Commun., 12, 319-322 (2006)]
  • Noeske, J., Richter, C., Stirnal, E., Schwalbe, H. & Wöhnert, J. Phosphate-group recognition by the aptamer domain of the thiamine pyrophosphate sensing riboswitch. ChemBioChem 7, 1451-1456 (2006)
  • Nören-Müller, A., Correa Jr., I.R., Prinz, H., Rosenbaum, C., Saxena, K., Schwalbe, H., Vestweber, D., Schunk, S., Schwarz, O., Schiewe, H. & Waldmann, H. Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proc. Natl. Acad. Sci. USA, 103, 10606-10611 (2006)
  • Raja, C., Ferner, J., Dietrich, U., Avilov, S., Ficheux, D., Darlix, J.-L., Rocquigny, H.d., Schwalbe, H. & Mély, Y. A tryptophan-rich hexapeptide inhibits nucleic acid destabilization chaperoned by the HIV-1 nucleocapsid protein. Biochemistry, 45, 9254-9265 (2006)
  • Rehm, S., Lenz, M.O., Mensch, S. Schwalbe, H. & Wachtveitl, J. Ultrafast spectroscopy of a photoswitchable 30-amino acid denovo synthesized peptide. Chem. Phys. 323, 28-35 (2006)
  • Rogov, V.V., Rogova, N.Y., Bernhard, F., Koglin, A., Löhr, F. & Dötsch, V. A new structural domain in the Escherichia coli RcsC hybrid sensor kinase connects histidine kinase and phosphoreceiver domains. J. Mol. Biol., 364, 68-79 (2006)
  • Schiemann, O. Bioanalytik, Spektrum Akademischer Verlag, Heidelberg, 2. Edition, 2006. Eds. F. Lottspeich & J.W. Engels
  • Schwarz, D., Klammt, C., Koglin, A., Löhr, F., Schneider, B., Dötsch, V. & Bernhard, F. Preparative scale cell-free expression systems: New tools for the large scale preparation of integral membrane proteins for functional and structural studies. Methods, 41, 355-369 (2006)
  • Serber, Z., Selenko, P., Hänsel, R., Reckel, S., Löhr, F., Ferrell, J., Wagner, G. & Dötsch, V. Investigating macromolecules inside cultured and injected cells by in-cell NMR spectroscopy. Nat. Prot., 1, 2701-2709 (2006)
  • Vogtherr, M., Saxena, K., Hoelder, S., Grimme, S., Betz, M., Schieborr, U., Pescatore, B., Robin, M., Langer, T., Wendt, K.U. & Schwalbe, H. NMR Charakterization of kinase p38 dynamics in free and ligand-bound forms. Angew. Chem. Int. Ed., 45, 993-997 (2006)
  • Wenter, P., Fürtig, B., Hainard, A., Schwalbe, H. & Pitsch, S. A caged uridine for the selective preparation of an RNA fold and determination of its refolding kinetics by real-time NMR. ChemBioChem, 7, 417-420 (2006)
  • Wirmer, J., Berk, H., Ugolini, R., Redfield, C. & Schwalbe, H. Characterization of the unfolded state of bovine α-lactalbumin and comparison with unfolded states of homologous proteins. Protein Science, 15, 1397-1407 (2006)

2005

  • Bertini, I., Gupta, Y.K., Luchinat, C., Parigi, G., Schlörb, C. & Schwalbe, H. NMR spectroscopic detection of protein protons and longitudinal relaxation rates between 0.01 and 50 MHz. Angew. Chem. Int. Ed., 44, 2223-2225 (2005)
  • Collins, E.S., Wirmer, J., Hirai, K., Tachibana, H., Segawa, S., Dobson, C.M. & Schwalbe, H. Characterization of disulfide-bond dynamics in non-native states of lysozyme and its disulfide deletion mutants by NMR. ChemBioChem, 6, 1619-1627 (2005)
  • Denysenkov, V.P., Prisner, T.F., Stubbe J. & Bennati, M. High-frequency 180 GHz PELDOR. Appl. Magn. Reson., 29, 375-384 (2005)
  • Diller, A., Alia, Roy, E., Gast, P., van Gorkum, H.J.M., Zaanem, J., de Groot, HJM, Glaubitz, C. & Matysik, J. Photo-CIDNP solid-state NMR on photosystems I and II: What makes P680 special? Photosynthesis Research, 84, 303-308 (2005)
  • Feilitzsch, T. von, Härter, P., Schiemann, O., Michel-Beyerle, M.E., Steiner, U.E. & Gilch, P. Magnetic field and temperature dependencies shed light on the recombination kinetics of a transition metal donor/acceptor system. J. Am. Chem. Soc., 127(43), 15228-15235 (2005)
  • Fritscher, J., Artin, E., Wnuk, S., Bar, G., Robblee, J.H., Kacprzak, S., Kaupp, M., Griffin, R.G., Bennati, M. & Stubbe, J. Structure of the nitrogen centered radical fromed during inactivation of E. coli ribonucleotide reductase by 2'-azido-2' deoxyuridine-5' diphosphate: Trapping of the 3'ketonucleotid. J. Am. Chem. Soc., 127(21), 7729-7738 (2005)
  • He, C., Hus, J.C., Sun, L.J., Zhou, P., Norman, D.P.G., Dötsch, V., Wei, H., Gross, J.D., Lane, W.S., Wagner, G. & Verdine, G.L. A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada. Mol. Cell, 20, 117-129 (2005)
  • Ilin, S., Hoskins, A., Ohlenschläger, O., Jonker, H.R.A, Schwalbe, H. & Wöhnert, J. Domain reorientation and induced fit upon RNA binding: Solution structure and dynamics of ribosomal protein L11 from Thermotoga maritima. ChemBioChem, 6, 1611-1618 (2005)
  • Jacobs, D.M., Grimme, S., Elshorst, B., Pescatore, B., Vogtherr, M., Betz, M., Schieborr, U., Langer, T., Saxena, K., Schwalbe, H. & Fiebig, K. Backbone NMR assignment of the C-terminal haemopexin-like domain (HPLD) of human matrix metalloproteinase MMP-13. J. Biomol. NMR, 32, 337-337 (2005)
  • Kirilina, E.P., Prisner, T.F., Bennati, M., Endeward, B., Dzuba, S.A. Fuchs, M., Möbius, K. & Schnegg, A. Molecular dynamics of nitroxides in glasses as studied by multi-frequency EPR. Mag. Res. Chem., 43, 119-129 (2005)
  • Kisselva, N., Khvorova, A., Westhof, E. & Schiemann, O. Binding of manganese(II) to a tertiary stabilized hammerhead ribozyme as studied by electron paramagnetic resonance spectroscopy. RNA, 11, 1-6 (2005)
  • Klammt, C., Schwarz, D., Fendler, K., Haase, W., Dötsch, V. & Bernhard, F. Evaluation of detergents fort he soluble expression of α-helical and β-barrel-type integral membrane proteins by a preparative scale individual cell-free expression system. FEBS J., 272, 6024-6038 (2005)
  • Koplin, J., Mu, Y., Richter, C., Schwalbe, H. & Stock., G. Structure and dynamics of an RNA tetraloop: A joint molecular-dynamics and NMR study. Structure, 13, 1255-1267 (2005)
  • Lancaster, C.R.D., Sauer, U.S., Groß, R., Haas, A., Graf, A.H.J., Schwalbe, H., Mäntele, W., Simon, J. & Madej, M.G. Experimental support for the "E-pathway hypothesis" of coupled transmembrane e- and H+ transfer in dihemic quinol: Fumarate reductase. Proc. Natl. Acad. Sci. USA, 102, 18860-18865 (2005)
  • Langer, T., Sreeramulu, S., Vogtherr, M., Elshorst,B., Betz, M., Schieborr, U., Saxena, K. & Schwalbe, H. Folding and activity of cAMP-dependent protein kinase mutants. FEBS Lett., 579, 4049-4054 (2005)
  • Löhr, F., Rogov, V.V., Shi, M., Bernhard, F. & Dötsch, V. Triple-resonance methods for complete resonance assignment or aromatic protons and directly bound heteronuclei in histidine and tryptophane residues. J. Biomol. NMR, 32, 309-328 (2005)
  • Lorch, M., Fahem, S., Kaiser, C., Weber, I., Mason, A.J., Bowie, J. & Glaubitz, C. How to prepare membrane proteins for solid-state NMR: A case study on the α-helical membrane protein DGK from E. coli. ChemBioChem, 6, 1693-1700 (2005)
  • Lorch, M., Lehner, I., Siarheyeva, A., Basting D., Pfleger, N., Manolikas, T. & Glaubitz, C. NMR and fluorescence spectroscopy approaches to seconndary and primary active multidrug efflux pumps. Biochem. Soc. Trans., 33, 873-877 (2005)
  • Manger, M., Scheck, M., Prinz, H., Feyen, F., Langer, T., Saxena, K., Schwalbe, H., Fürstner, A. & Waldmann, H. Discovery of mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach. ChemBioChem, 6, 1749-1753 (2005)
  • Mason, A.J., Lopez, J.J., Beyermann, M. & Glaubitz, C. A spectroscopic Study of the membrane interaction of tuberoinfundibular peptide of 39 residues (TIP39). BBA Biomembranes, 1714, 1-10 (2005)
  • Mason, A.J., Martinez, A., Glaubitz, C., Danos, O. & Kichler, A. and Bechinger, B. The antibiotic and DNA-transfecting peptide LAH4 selectively associates with, and disorders, anionic lipids in mixed membranes. FASEB J, 19, 320-322 (2005)
  • Mason, A.J., Turner, G. & Glaubitz, C. Conformational heterogeneity of transmembrane residues after the Schiff base reprotonation of bacteriorhodopsin - 15N CPMAS NMR of D85N/T170C membranes. FEBS J, 272, 2152-2164 (2005)
  • Noeske, J., Richter, C., Grundl, M.A., Nasiri, H.R., Schwalbe, H. & Wöhnert J. An intermolecular base triple as the basis of ligand specificity and affinity in the guanine and adenine sensing riboswitch RNAs. Proc. Natl. Acad. Sci. USA, 104, 1372-1377 (2005)
  • Nozinovic, S., Nachtsheim, B., Scheuermann, S., Schnorr, J., Silvers, R., Wagner, M. & Schwalbe, H. Learning problem-solving thinking in group work. Nachrichten aus der Chemie, 53, 978-980 (2005)
  • Petrosky, K.Y., Ou, H.D., Löhr, F., Dötsch, V. & Lim, W.A. A general model for preferential hetero-oligomerization of L27 domains: Mechanism underlying directed assembly of superamolecular signaling complexes. J. Biol. Chem., 280, 38528-38536 (2005)
  • Saxena, K., Elshorst, B., Berk, H., Betz, M., Grimme, S., Langer, T., Pescatore, B., Schieborr, U., Vogtherr, M. & Schwalbe, H. Backbone NMR assignment of the low-molecular-weight protein tyrosine phosphatase (MPtpA) from Mycobacterium tuberculosis. J. Biomol. NMR, 33, 136-136 (2005)
  • Saxena, K., Jacobs, D.M., Vogtherr, M., Grimme, S., Elshorst, B., Pescatore, B., Betz, M., Schieborr, U., Langer, T., Schwalbe, H. & Fiebig, K. Backbone NMR assignment of the human E2 ubiquitin conjugating enzyme UbcH5α (F72K,F82S) double mutant. J. Biomol. NMR, 32, 338-338 (2005)
  • Schieborr, U., Vogtherr, M., Elshorst, B., Betz, M., Grimme, S., Pescatore, B., Langer, T., Saxena, K. & Schwalbe, H. How much NMR data is required to determine a protein–ligand complex structure? ChemBioChem, 6, 1891-1898 (2005)
  • Schlörb, C., Ackermann, K., Richter, C., Wirmer, J. & Schwalbe, H. Heterologous expression of hen egg white lysozyme and resonance assignment of tryptophan side chains in its non-native states. J. Biomol. NMR, 33, 95-104 (2005)
  • Schwalbe, H. & Wirmer, J. Protein misfolding disease: Overview of liquid and solid state high resolution NMR studies. In Handbook of Modern Magnetic Resonance (Ed. W. Graham), London, Kluwer (2005)
  • Spoerner, M., Prisner, T.F., Bennati, M., Hertel, M., Weiden, N., Schweins, T. & Kalbitzer, H.R. Conformational states of human H-Ras detected by high-field EPR. ENDOR and 31P NMR spectroscopy. Mag. Res. Chem., 43, 74-83 (2005)
  • Sreeramulu, S., Kumar, J., Richter, C., Vogtherr, M., Saxena, K., Langer, T. & Schwalbe, H. 1H, 13C and 15N backbone resonance assignment of the Hsp90 binding domain of human Cdc37. J. Biomol. NMR, 32, 262 (2005)
  • Vogtherr, M., Saxena, K., Grimme, S., Betz, M., Schieborr, U., Pescatore, B., Langer, T. & Schwalbe, H. NMR backbone assignment of the mitogen-activated protein (MAP) kinase p38. J. Biomol. NMR, 32(2)175 (2005)
  • Wenter, P., Fürtig, B., Hainard, A., Schwalbe, H. & Pitsch, S. Kinetics of photoinduced RNA refolding by real-time NMR spectroscopy. Angew. Chem. Int. Ed., 44, 2600-2603 (2005); [Angew. Chem., 117, 2656-2659 (2005)]
  • Wirmer, J., Schlörb, C. & Schwalbe, H. Conformation and dynamics of nonnative states of proteins studied by NMR spectroscopy. In Protein Folding Handbook (Ed. J. Buchner & T. Kiefhaber), WILEY-VCH, Weinheim, pp. 737-803 (2005)

2004

  • Duchardt, E., Richter, C., Ohlenschläger, O., Görlach, M., Wöhnert, J. & Schwalbe, H. Determination of the glycosidic bond angle χ in RNA from cross-correlated relaxation of CH dipolar coupling and N-chemical shift anisotropy. J. Am. Chem. Soc., 126, 1962-1970 (2004)
  • Fürtig, B., Richter, C., Bermel, W. & Schwalbe, H. New NMR experiments for RNA nucleobase resonance assignment and chemical shift analysis of an RNA UUCG tetraloop. J. Biomol. NMR, 28, 69-79 (2004)
  • Giese, B., Carl, B., Carl, T., Carell, T., Behrens, C., Hennecke, U., Schiemann, O. & Feresin, E. Excess electron transport through DNA: A single electron repairs more than one UV-induced lesion. Angew. Chem. Int. Ed., 43, 1848-1851 (2004)
  • Giroglou, T., Cinatl Jr., J., Rabenau, H., Drosten, Ch., Schwalbe, H., Doerr, H.W. & von Laer, D. Retroviral vectors pseudotyped with severe acquired respiratory syndrome (SARS) coronavirus S protein. J. Virol., 78, p. 9007-9015 (2004)
  • Klammt, C., Löhr, F., Schäfer, B., Haase, W., Dötsch, V., Rüterjans, H., Glaubitz, C. & Bernhard, F. High level cell-free expression and specific labeling of integral membrane proteins. Eur. J. Biochem., 271, 568-580 (2004)
  • Klein-Seetharaman, J., Yanamala, N.V.K., Javeed, F., Reeves, P.J., Getmanova, E.V., Loewen, M.C., Schwalbe, H. & Khorana, H.G. Differential dynamics in the G protein-coupled receptor rhodopsin revealed by solution NMR. Proc. Natl. Acad. Sci. USA, 101, 3409-3413 (2004)
  • Langer, T., Vogtherr, M., Elshorst, B., Betz, M., Schieborr, U., Saxena, K. & Schwalbe, H. NMR backbone assignment of a protein kinase catalytic domain by a combination of several approaches: Application to the catalytic subunit of cAMP-dependent kinase. ChemBioChem, 5, 1508-1516 (2004)
  • Maly, T., MacMillan, F., Zwicker, K., Kashani-Poor, N., Brandt, U. & Prisner, T.F. Relaxation filtered hyperfine (REFINE) spectroscopy: A novel tool for studying overlapping biological EPR signals applied to mitochondrial Complex I. Biochemistry, 43(13), 3969-3978 (2004)
  • Mason, A.J., Grage, S.L., Straus, S.K., Glaubitz, C. & Watts, A. Identifying anisotropic constraints in multiply labeled bacteriorhodopsin by N-15 MAOSS NMR: A general apporach to structural studies of membrane proteins. Biophys. J., 86, 1610-1617 (2004)
  • Mason, A.J., Siarheyeva, A., Haase, W., Lorch, M., van Veen, H. & Glaubitz, C. Amino acid type selctive isotpe labelling of the multidrug ABC transporter LmrA for solid-state NMR studies. FEBS Lett, 568, 117-121 (2004)
  • Petrenko, A., Maniero, A.L., v.Tol, J., MacMillan, F., Li, Y., Brunel, L.C. & Redding, K. A high-field EPR study of P700+. in wild-type and mutant Photosystem I from Chlamydomonas reinhardtii. Biochemistry, 43(7), 1781-1786 (2004)
  • Prisner, T.F. Pulsed high-frequency EPR: Biological applications. Biolog. Magn. Reson., 22, 249-272 (2004)
  • Rogov, V.V., Bernhard, F., Löhr, F. & Dötsch, V. Letter to the editor: Assignment of 1H, 13C and 15N resonances of the Escherichia coli YojN histidine-phosphotransferase (HPt) domain. J. Biomol. NMR, 30, 103-104 (2004)
  • Rogov, V.V., Bernhard, F., Löhr, F. & Dötsch, V. Solution structure of the Escherichia coli YojN histidine phosphotransferase domain and its interaction with cognate phosphoryl receiver domains. J. Mol. Biol., 343, 1035-1048 (2004)
  • Schiemann, O., Feresin, E., Carl, T. & Giese, B. 4´-Pivaloyl substituted thymidine as a precursor for the thymyl radical. An EPR spectroscopic study. Chem.Phys.Chem., 5, 270-274 (2004)
  • Schiemann, O., Plackmeyer, J., Fritscher, J. & Elschenbroich, C. Trovacenyl-based organometallic triradicals: Spin frustration, competing interactions and redox splitting. Appl. Magn. Reson., 26, 171-182 (2004)
  • Serber, Z., Straub, W., Corsini, L., Nomura, A.M., Shimba, N., Craik, C.S. Ortiz de Montellano, P. & Dötsch, V. Methyl groups as probes for proteins and complexes in In-Cell NMR experiments. J. Am. Chem. Soc., 126, 7119-7125 (2004)
  • Shimba, N., Kovacs, H., Stern, A.S., Nomura, A.M., Shimada, I., Hoch, J.C., Craik, C.S. & Dötsch, V. Optimization of 13C direct detection NMR methods. J. Biomol. NMR, 30, 175-179 (2004)
  • von Buuren, B.N.M., Schleucher, J., Wittmann, V., Griesinger, C., Schwalbe, H. & Wijmenga, S.S. NMR spectroscopic determination of the solution structure of a branched nucleic acid from residual dipolar couplings by using isotopically labeled nucleotides. Angew. Chem. Int. Ed., 116, 189-194 (2004)
  • Wirmer, J., Schlörb, C., Klein-Seethamaran, J., Hirano, R., Ueda, T., Imoto, T. & Schwalbe, H. Modulation of compactness and long-range interactions of unfolded lysozyme by single point mutations. Angew. Chem. Int. Ed., 43, 5780-5785 (2004)

2003

  • Beyer, M., Fritscher, J., Feresin, E. & Schiemann, O. Synthesis of novel aromatic nitroxides as potential DNA intercalators. An EPR spectroscopical and DFT computational study. J. Org. Chem., 68, 2209-2215 (2003)
  • Elshorst, B., Jacobs, D.M., Schwalbe, H. & Langer, T. Letter to the editor: 1H, 13C and 15N backbone resonance assignment of the integrin α2 I-domain. J. Biomol. NMR, 27, 191-192 (2003)
  • Fürtig, B., Richter, C., Wöhnert, J. & Schwalbe, H. NMR-spectroscopy of RNA. [Chembiochem, 4, 936-962 (2003)]
  • Grimaldi, S., Ostermann, T., Weiden, N., Mogi, T., Miyoshi, H., Ludwig, B., Michel, H., Prisner, T.F. & MacMillan, F. Asymmetric binding of the high-affinity QH-. ubisemiquinone in quinol oxidase (bo3) from E. coli studied by multifrequency EPR spectroscopy. Biochemistry, 42(19), 5632 - 5639 (2003)
  • Ilin, S., Hoskins, A., Schwalbe, H. & Wöhnert, J. Letter to the editor: NMR assignment of the full-length ribosomal protein L11 from Thermotoga maritima. J. Biomol. NMR, 25, 163-164 (2003)
  • Prisner, T., Lyubenova, S., Atabay, Y., MacMillan, F., Kröger, A. & Klimmek, O. Multifrequency cw-EPR investigation of the catalytic molybdenum cofactor of polysulfide reductase from Wolinella succinogenes. J. Biol. Inorg. Chem., 8(4), 419 - 426 (2003)
  • Pustowka, A., Dietz, J., Ferner, J., Baumann, M., Landersz, M., Königs, C., Schwalbe, H. & Dietrich, U. Identification of peptide ligands for target RNA structures derived from the HIV-1 packaging signal ψ by screening phage-displayed peptide libraries. ChemBioChem, 4, 1093-1097 (2003)
  • Schiemann, O., Fritscher, J., Kisseleva, N., Sigurdsson, S.T & Prisner, T.F. Structural investigation of a high affinity MnII binding site in the hammerhead ribozyme by EPR spectroscopy and DFT calculations. Effects of neomycine-B on metal-ion binding. ChemBioChem, 4, 1057-1065 (2003)
  • Shimba, N., Serber, Z., Ledwidge, R., Miller, S.M., Craik, C. & Dötsch, V. Quantitative identification of the protonation state of histidines in vitro & in vivo. Biochemistry, 42, 9227-9234 (2003)
  • Shimba, N., Stern, A.S., Craik, C.S., Hoch, J.C. & Dötsch, V. Elimination of 13Ca splitting in protein NMR spectra by deconvolution with maximum entropy reconstruction. J. Am. Chem. Soc., 125, 2382-2383 (2003)
  • Schwalbe, H. Kurt Wüthrich, the ETH Zürich, and the development of NMR spectroscopy for the investigation of structure, dynamics and folding of proteins. ChemBioChem, 4, 135-142 (2003)
  • Schwalbe, H. & Kessler, H. 900-MHz-NMR-Spektrometer in München und Frankfurt. Nachrichten aus der Chemie, 51, 412-417 (2003)
  • Vogtherr, M., Grimme, S., Pescatore, B. & Schwalbe, H. Letter to the editor: 1H, 13C and 15N backbone resonance assignment of the VASP EVH1 domain. J. Biomol. NMR, 27, 189-190 (2003)
  • Wöhnert, J., Franz, K.J., Nitz, M., Imperiali, B. & Schwalbe, H. Protein alignment by a coexpressed lanthanide-binding tag for the measurement of residual dipolar couplings. J. Am. Chem. Soc., 125, 13338-13339 (2003)
  • Wöhnert, J., Görlach, M. & Schwalbe, H. Triple resonance experiments for the simultaneous correlation of H6/H5 and exchangeable protons of pyrimidine nucleotides in 13C,15N-labeled RNA applicable to larger RNA molecules. J. Biomol. NMR, 26, 79-83 (2003)

2002

  • Albert, M., Seebach, D., Duchardt, E. & Schwalbe, H. Synthesis and NMR analysis in solution of oligo(3-hydroxyalkanoic acid) derivatives with the side chains of alanine, valine, and leucine (β-depsides): Coming full circle from PHB to β-peptides to PHB. Helv. Chim. Acta, 85, 633-658 (2002)
  • Duijf, P.H.G., Vanmolkot, K.R.J., Propping, P., Friedl, W., Krieger, E., McKeon, F., Dötsch, V., Brunner, H.G. & van Bokhoven, H. Gain-of-function mutation in ADULT syndrome reveals the presence of a second transactivation domain in p63. Hum. Mol. Genet., 11, 799-804 (2002)
  • Fuhs, M., Schnegg, A., Prisner, T.F., Köhne, I., Hanley, J., Rutherford A.W. & Möbius, K. Orientation selection in photosynthetic PS I multilayers: structural investigation of the charge separated state P700+. A1-. by high-field/ high-frequency time-resolved EPR at 3.4 T/95 GHz. BBA Bioenergetics, 1556, 81-88 (2002)
  • Fritscher, J., Beyer, M. & Schiemann, O. Synthesis, crystal structure and magnetic properties of a novel nitroxide biradical. Theoretical investigation of the exchange mechanisms. Chem. Phys. Lett., 364, 393-401 (2002)
  • Gee, P.J., Hamprecht, F.A., Schuler, L.D., Gunsteren, W.F.V., Duchardt, E., Schwalbe, H., Albert, M. & Seebach, D. A molecular dynamics simulation study of the conformational preferences of oligo(3-hydroxyalcanoic acids) in chloroform solution. Helv. Chim. Acta, 85, 618-632 (2002)
  • Grimaldi, S., MacMillan, F., Ostermann, T., Ludwig, B., Michel, H., Mogi, T., Miyoshi, H., Weiden, N., Dinsem, K.P. & Prisner, T.F. QH-. quinone binding pocket in quinol oxidase studied by EPR spectroscopy. Biochim. Biophys. Acta, EBEC Short Reports, 12, 87 (2002)
  • Ilin, S., Schlönvogt, I., Ebert, M.O., Jaun, B. & Schwalbe, H. Comparison of the NMR solution structures of pyranosyl-RNA and its nucleo-δ-peptides analogues. ChemBioChem, 3, 93-99 (2002)
  • Klein-Seetharaman, J., Oikawa, M., Grimshaw, S.B., Wirmer, J., Duchardt, E., Ueda, T., Imoto, T., Smith, L.J., Dobson, C.M. & Schwalbe, H. Long-range interactions within a non-native protein Science 295, 1719-1722 (2002); siehe auch: Perspectives article: Baldwin, R.L. "Making a network of hydrophobic cluster. Science, 295, 1657-1658 (2002)
  • Klein-Seetharaman, J., Reeves, P.J., Loewen, M.C., Getmanova, E.V., Chung, J., Wright, P.E., Schwalbe, H. & Khorana, H.G. Application of Solution NMR spectroscopy of [α-15N]lysine-labeled rhodopsin: The single peak observed in both conventional and TROSY-type HSQC spectra is ascribed to Lys-339 in the carboxyl-terminal peptide sequence. Proc. Natl. Acad. Sci. USA., 99, 3452-3457 (2002)
  • Maly, Th., MacMillan, F., Zwicker, K., Kashani-Poor, N., Grgic, L., Brandt, U. & Prisnerm, T.F. Complex I studied by pulsed EPR Spectroscopy. Biochim. Biophys. Acta, EBEC Short Reports, 12, 191 (2002)
  • Schnegg, A., Fuhs, M., Rohrer, M., Lubitz, W., Prisner, T.F. & Möbius,K. Molecular dynamics of QA–•QB–•in bacterial reaction centers studied by pulsed high-field EPR at 95 GHz. J. Phys. Chem. B., 106, 9454-9462 (2002)
  • Serber, Z., Lai, H.C., Yang, A., Yang, A., Ou, H.D., Sigal, M., Kelly, A.E., Darimont, B.D., Duijf, P.H.G., van Bokhoven, H., McKeon, F. & Dötsch, V. A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism. Molecular Cellular Biology, 22, 8601-8611 (2002)
  • Spooner, P.J.R., Sharples, J.M., Verhoeven, M.A., Lugtenburg, J., Glaubitz, C. & Watts, A. Relative orientation between the beta-ionone ring and the polyene chain for the chromophore of rhodopsin in native membranes. Biochemistry, 41, 7549-7555 (2002)
  • Schwalbe, H. & Wess, G. Editorial: Dissecting G-protein coupled receptors: Structure, function and ligand interaction. ChemBioChem, 3, 915-919 (2002)
  • Weber, A., Schiemann, O., Bode, B. & Prisner, T.F. PELDOR at S- and X-Band Frequencies and the separation of exchange coupling from dipolar coupling. J. Magn. Res., 157, 277-285 (2002)
  • Wirmer, J. & Schwalbe, H. Angular dependence of 1J(Ni,Cαi) and 2J(Ni,Cα(i-1)) coupling constants measured in J-modulated HSQCs J. Biomol. NMR, 23, 47-55 (2002)
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